IPhD in Ageing, Health and Welfare

Individual research projects are tailored around the expertise of principal investigators within our Schools. A variety of approaches are used, including experiments in field and laboratory conditions, epidemiology, mathematical, computational and statistical modelling, bioinformatics, physiology, molecular biology, parasitology, immunology and polyomics (genomics, transcriptomics, proteomics, metabolomics). Basic and applied science projects are available for study, as are field-based projects with research programs underway in both the UK and overseas.
Ageing affects almost all species, but the rate at which it occurs varies considerably among and within species. People are now living much longer than previous generations, with ageing being the major risk factor for many diseases. This has given rise to the concept of not only our life span but also our health span which is the length of a disease free life. We know that the environment we live in can influence how we age. It is now increasingly recognised that the ageing process and its' associated disease risk can be 'set up or programmed by events experienced before we are born, prenatal programming, or during postnatal development i.e. pre and peripubertal as well as in adult life. Consequently, understanding why we age, how we age, the factors responsible for variation in ageing and longevity, and the impact ageing has on health and wellbeing is a major challenge in science today.
We are uniquely placed to employ a highly integrative, comparative and collaborative approach for the study of ageing, health and animal welfare. We study ageing at the molecular, cellular and organism level, in the field and in the laboratory, and combine mechanistic, functional and applied perspectives. We currently use a range of interventions and techniques to examine key issues in both laboratory and field settings. Using these approaches we are interested in a range of factors (e.g. stress, pollution, chronobiology, diet, growth pattern, metabolism, reproduction, epidemiology, immunity), how they are affected by ageing and their impact on human and animal health.
Given the rapidly expanding human population, a second major societal challenge is the requirement to produce sufficient safe, nutritious, affordable and sustainable foodstuffs. We are particularly interested in ways to sustain efficient animal production in a manner which protects animal health and welfare, while mitigating against pests and disease and reducing environmental impact. We have expertise in the development and application of behavioural, physiological and neurophysiological approaches to welfare assessment in managed and wild animals.