Faculty of the Division of Cell and Developmental Biology (CDB) pursue research aimed at detailed understanding of: the structure and function of cellular components, such as membranes, organelles, chromosomes and the cytoskeleton, cellular processes, such as epithelial transport, cell motility, mitosis, protein targeting and secretion, stem cell plasticity, and eukaryotic cell cycle control, tumor biology, cellular physiology, the origin of cell polarity, and the molecular and cellular basis for axis formation, morphogenetic movements, fate determination, and gene regulation during embryogenesis and cellular differentiation. These issues are being addressed in systems as diverse as yeast, fruit flies, worms, sea urchins, frogs, mice and mammalian cells in culture, and these studies exploit techniques ranging from molecular biology and microinjection to digital imaging and mathematical modeling. Specialized equipment for confocal fluorescence microscopy, video imaging, and computer simulations are available in shared core facilities in the Life Sciences Addition where many of the faculty are housed.