The graduate program in biomedical informatics and computational biology (BICB) offers course work in five core areas: 1) biochemistry, molecular and cell biology, 2) database, data mining, and computing, 3) informatics, analysis, and machine learning, 4) mathematics, biostatistics, and statistics, and 5) computational and systems biology. In addition, students select courses from a diverse set of fields, including chemistry, chemical engineering, physics, biophysics, structural biology, imaging, signal processing, and clinical and translational sciences. The curriculum is individualized to fit the student's interest and research direction. Prior coursework may be used to fill the requirements if appropriate. Students may pursue a minor in a different program. All students receive training in ethics, leadership, and management, including legal and intellectual property issues and entrepreneurship. Those interested in academic careers have the opportunity to participate in development programs that focus on aspects of teaching and learning. The M.S. is offered under two plans: Plan A (with thesis), and Plan B (with project). Plan A is considered suitable for students planning to pursue careers that require a limited research experience or those planning to continue their education in a Ph.D. program. It is also suitable for students with full-time employment whose thesis can be related to their work assignments. Plan B is suitable for students planning to work in settings where technical knowledge is more germane than research experience.